8WUL
Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, A, E, G | TCR alpha chain | polymer | 198 | 22105.7 | 4 | Mus musculus | ||
2 | D, B, F, H | TCR beta chain | polymer | 239 | 27321.8 | 4 | Mus musculus | ||
3 | L, I, O, R | MHC class I antigen | polymer | 274 | 31725.9 | 4 | UniProt (A0A6M6CC39) Pfam (PF00129) Pfam (PF07654) In PDB | Homo sapiens (human) | HLA-A*1101 |
4 | M, J, P, S | Beta-2-microglobulin | polymer | 99 | 11748.2 | 4 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | |
5 | N, K, Q, T | KRAS-G12V nonamer peptide | polymer | 9 | 786.0 | 4 | Homo sapiens | ||
6 | water | water | 18.0 | 403 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 20 |
Total formula weight | 374749.9 | |
All* | Total formula weight | 374749.9 |