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8WUL

Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1C, A, E, GTCR alpha chainpolymer19822105.74Mus musculus
2D, B, F, HTCR beta chainpolymer23927321.84Mus musculus
3L, I, O, RMHC class I antigenpolymer27431725.94UniProt (A0A6M6CC39)
Pfam (PF00129)
Pfam (PF07654)
In PDB
Homo sapiens (human)HLA-A*1101
4M, J, P, SBeta-2-microglobulinpolymer9911748.24UniProt (P61769)
Pfam (PF07654)
In PDB
Homo sapiens (human)
5N, K, Q, TKRAS-G12V nonamer peptidepolymer9786.04Homo sapiens
6waterwater18.0403Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains20
Total formula weight374749.9
All*Total formula weight374749.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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