8T1C
Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA
Summary for 8T1C
Entry DOI | 10.2210/pdb8t1c/pdb |
Related | 8T1B |
EMDB information | 40958 40959 |
Descriptor | Transient receptor potential cation channel subfamily V member 4-Enhanced green fluorescent protein chimera, Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | transient receptor potential v family member 4, trp, channel, trpv4, trp channels, membrane protein, gtpase, transforming protein rhoa, rhoa, ankyrin repeat domain, gdp, guanosine diphosphate |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 149960.30 |
Authors | Nadezhdin, K.D.,Talyzina, I.A.,Neuberger, A.,Sobolevsky, A.I. (deposition date: 2023-06-02, release date: 2023-07-05) |
Primary citation | Nadezhdin, K.D.,Talyzina, I.A.,Parthasarathy, A.,Neuberger, A.,Zhang, D.X.,Sobolevsky, A.I. Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14:3733-3733, 2023 Cited by PubMed: 37353478DOI: 10.1038/s41467-023-39346-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.49 Å) |
Structure validation
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