8OPM
Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (closed state)
Summary for 8OPM
Entry DOI | 10.2210/pdb8opm/pdb |
Related | 8OHN 8OPN 8OPO |
EMDB information | 17076 |
Descriptor | Spike glycoprotein,General control transcription factor GCN4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | virus, coronavirus, hku1, spike, glycoprotein, membrane fusion, viral protein |
Biological source | Human coronavirus HKU1 More |
Total number of polymer chains | 3 |
Total formula weight | 469285.15 |
Authors | Pronker, M.F.,Creutznacher, R.,Hurdiss, D.L. (deposition date: 2023-04-07, release date: 2023-08-02, Last modification date: 2023-12-13) |
Primary citation | Pronker, M.F.,Creutznacher, R.,Drulyte, I.,Hulswit, R.J.G.,Li, Z.,van Kuppeveld, F.J.M.,Snijder, J.,Lang, Y.,Bosch, B.J.,Boons, G.J.,Frank, M.,de Groot, R.J.,Hurdiss, D.L. Sialoglycan binding triggers spike opening in a human coronavirus. Nature, 624:201-206, 2023 Cited by PubMed: 37794193DOI: 10.1038/s41586-023-06599-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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