8JWY
Crystal structure of A2AR-T4L in complex with 2-118
Summary for 8JWY
Entry DOI | 10.2210/pdb8jwy/pdb |
Descriptor | Adenosine receptor A2a,Endolysin, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, CHOLESTEROL, ... (7 entities in total) |
Functional Keywords | adenosine receptor 2a, gpcr, inhibitor, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 60361.95 |
Authors | |
Primary citation | Weng, Y.,Yang, X.,Zhang, Q.,Chen, Y.,Xu, Y.,Zhu, C.,Xie, Q.,Wang, Y.,Yang, H.,Liu, M.,Lu, W.,Song, G. Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors. Sci China Life Sci, 67:986-995, 2024 Cited by PubMed: 38319473DOI: 10.1007/s11427-023-2459-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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