8JWY
Crystal structure of A2AR-T4L in complex with 2-118
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIfSLLAIAIDRYIaI |
| Chain | Residue | Details |
| A | SER90-ILE106 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=1 |
| Chain | Residue | Details |
| A | VAL8-TRP32 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:18832607 |
| Chain | Residue | Details |
| A | LEU33-ASN42 | |
| A | ASP101-ARG120 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=2 |
| Chain | Residue | Details |
| A | TYR43-ILE66 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:18832607 |
| Chain | Residue | Details |
| A | SER67-CYS77 | |
| A | ASN144-PRO173 | |
| A | CYS406-PRO413 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=3 |
| Chain | Residue | Details |
| A | LEU78-ILE100 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=4 |
| Chain | Residue | Details |
| A | ALA121-TRP143 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=5 |
| Chain | Residue | Details |
| A | MET174-LEU198 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=6 |
| Chain | Residue | Details |
| A | LEU382-PHE405 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=7 |
| Chain | Residue | Details |
| A | LEU414-TYR437 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO |
| Chain | Residue | Details |
| A | GLU169 | |
| A | ASN400 | |
| A | SER424 | |
| A | HIS425 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN154 |
