8ITG

Crystal structure of lasso peptide epimerase MslH in complexed with precursor peptide variant MslAW21G

Summary for 8ITG

Entry DOI	10.2210/pdb8itg/pdb
Descriptor	Poly-gamma-glutamate synthesis protein (Capsule biosynthesis protein), Tricyclic peptide MS-271, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	epimerase, mslh, msla, lasso peptide, ripps, ms-271, isomerase
Biological source	Streptomyces griseorubiginosus More
Total number of polymer chains	2
Total formula weight	51920.67
Authors	Nakashima, Y.,Hiroyuki, M. (deposition date: 2023-03-22, release date: 2023-06-21, Last modification date: 2023-08-23)
Primary citation	Nakashima, Y.,Kawakami, A.,Ogasawara, Y.,Maeki, M.,Tokeshi, M.,Dairi, T.,Morita, H. Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism. Nat Commun, 14:4752-4752, 2023 Cited by PubMed: 37550286 DOI: 10.1038/s41467-023-40232-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation