8I5G

Structure of human Nav1.7 in complex with PF-05089771

Summary for 8I5G

• Entry DOI: 10.2210/pdb8i5g/pdb
• EMDB information: 35194
• Descriptor: Sodium channel subunit beta-1, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (12 entities in total)
• Functional Keywords: inhibitor complex., membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 285395.22

Authors

Wu, Q.R.,Yan, N. (deposition date: 2023-01-25, release date: 2023-06-14, Last modification date: 2023-11-08)

• Primary citation: Wu, Q.,Huang, J.,Fan, X.,Wang, K.,Jin, X.,Huang, G.,Li, J.,Pan, X.,Yan, N.; Structural mapping of Na v 1.7 antagonists.; Nat Commun, 14:3224-3224, 2023; PubMed: 37270609; DOI: 10.1038/s41467-023-38942-3

Experimental method

ELECTRON MICROSCOPY (2.7 Å)