8HG1

The structure of MPXV polymerase holoenzyme in replicating state

Summary for 8HG1

• Entry DOI: 10.2210/pdb8hg1/pdb
• EMDB information: 34731
• Descriptor: DNA polymerase, E4R, DNA polymerase processivity factor component A20, ... (7 entities in total)
• Functional Keywords: mpxv, polymerase, replication, replication-dna complex, replication/dna
• Biological source: Monkeypox virus (monkeypox); More
• Total number of polymer chains: 5
• Total formula weight: 214116.73

Authors

Peng, Q.,Xie, Y.F.,Kuai, L.,Wang, H.,Qi, J.X.,Gao, F.,Shi, Y. (deposition date: 2022-11-13, release date: 2022-12-21, Last modification date: 2023-01-18)

• Primary citation: Peng, Q.,Xie, Y.,Kuai, L.,Wang, H.,Qi, J.,Gao, G.F.,Shi, Y.; Structure of monkeypox virus DNA polymerase holoenzyme.; Science, 379:100-105, 2023; PubMed: 36520947; DOI: 10.1126/science.ade6360

Experimental method

ELECTRON MICROSCOPY (2.8 Å)