8HF0

DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state

Summary for 8HF0

• Entry DOI: 10.2210/pdb8hf0/pdb
• EMDB information: 34707
• Descriptor: Dicer-2, isoform A, Loquacious, isoform D, LD06392p, ... (4 entities in total)
• Functional Keywords: ribonuclease, double stranded rna, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 7
• Total formula weight: 538040.20

Authors

Su, S.,Wang, J.,Wang, H.W.,Ma, J. (deposition date: 2022-11-09, release date: 2023-09-06)

• Primary citation: Deng, T.,Su, S.,Yuan, X.,He, J.,Huang, Y.,Ma, J.,Wang, J.; Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.; Nat Commun, 14:5228-5228, 2023; PubMed: 37633971; DOI: 10.1038/s41467-023-40919-1

Experimental method

ELECTRON MICROSCOPY (3.72 Å)