8GVX

Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2

Summary for 8GVX

• Entry DOI: 10.2210/pdb8gvx/pdb
• Related: 7X6I
• EMDB information: 34301 34394 34396
• Descriptor: Short transient receptor potential channel 5, Guanine nucleotide-binding protein G(i) subunit alpha-3, PHOSPHATIDYLETHANOLAMINE, ... (8 entities in total)
• Functional Keywords: trp, transient receptor potential, metal transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 535181.28

Authors

Won, J.,Jeong, H.,Lee, H.H. (deposition date: 2022-09-16, release date: 2023-05-24)

• Primary citation: Won, J.,Kim, J.,Jeong, H.,Kim, J.,Feng, S.,Jeong, B.,Kwak, M.,Ko, J.,Im, W.,So, I.,Lee, H.H.; Molecular architecture of the G alpha i -bound TRPC5 ion channel.; Nat Commun, 14:2550-2550, 2023; PubMed: 37137991; DOI: 10.1038/s41467-023-38281-3

Experimental method

ELECTRON MICROSCOPY (3.91 Å)