8FN8

Crystal structure of the C-terminal Fg domain of TNC with the single FN domain of PTPRZ

Summary for 8FN8

Entry DOI	10.2210/pdb8fn8/pdb
Descriptor	Tenascin, Receptor-type tyrosine-protein phosphatase zeta, CALCIUM ION, ... (4 entities in total)
Functional Keywords	complex, receptor protein tyrosine phosphatase, extracellular matrix, fibronectin type iii, fibrinogen, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	38337.66
Authors	Bouyain, S. (deposition date: 2022-12-27, release date: 2023-07-12, Last modification date: 2023-10-25)
Primary citation	Sinha, A.,Kawakami, J.,Cole, K.S.,Ladutska, A.,Nguyen, M.Y.,Zalmai, M.S.,Holder, B.L.,Broerman, V.M.,Matthews, R.T.,Bouyain, S. Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets. J.Biol.Chem., 299:104952-104952, 2023 Cited by PubMed: 37356715 DOI: 10.1016/j.jbc.2023.104952 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation