8FAC

Structure of the leucine-rich repeat kinase 1 monomer

Summary for 8FAC

Entry DOI	10.2210/pdb8fac/pdb
EMDB information	28949 28950 28951
Descriptor	Leucine-rich repeat serine/threonine-protein kinase 1, GUANOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywords	kinase, lrrk, multi-domain protein, gtpase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	229999.56
Authors	Metcalfe, R.D.,Martinez Fiesco, J.A.,Zhang, P. (deposition date: 2022-11-25, release date: 2023-08-16)
Primary citation	Metcalfe, R.D.,Martinez Fiesco, J.A.,Bonet-Ponce, L.,Kluss, J.H.,Cookson, M.R.,Zhang, P. Structure and regulation of full-length human leucine-rich repeat kinase 1. Nat Commun, 14:4797-4797, 2023 Cited by PubMed: 37558661 DOI: 10.1038/s41467-023-40532-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.92 Å)

Structure validation