8EEV

Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20

Summary for 8EEV

• Entry DOI: 10.2210/pdb8eev/pdb
• EMDB information: 28059 28060
• Descriptor: Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain (3 entities in total)
• Functional Keywords: venezuelan equine encephalitis virus, neutralizing antibody, veev, virus like particle-immune system complex, virus like particle/immune system
• Biological source: Venezuelan equine encephalitis virus; More
• Total number of polymer chains: 12
• Total formula weight: 979502.53

Authors

Tsybovsky, Y.,Pletnev, S.,Verardi, R.,Roederer, M.,Kwong, P.D. (deposition date: 2022-09-07, release date: 2023-07-19)

• Primary citation: Sutton, M.S.,Pletnev, S.,Callahan, V.,Ko, S.,Tsybovsky, Y.,Bylund, T.,Casner, R.G.,Cerutti, G.,Gardner, C.L.,Guirguis, V.,Verardi, R.,Zhang, B.,Ambrozak, D.,Beddall, M.,Lei, H.,Yang, E.S.,Liu, T.,Henry, A.R.,Rawi, R.,Schon, A.,Schramm, C.A.,Shen, C.H.,Shi, W.,Stephens, T.,Yang, Y.,Florez, M.B.,Ledgerwood, J.E.,Burke, C.W.,Shapiro, L.,Fox, J.M.,Kwong, P.D.,Roederer, M.; Vaccine elicitation and structural basis for antibody protection against alphaviruses.; Cell, 186:2672-2689.e25, 2023; PubMed: 37295404; DOI: 10.1016/j.cell.2023.05.019

Experimental method

ELECTRON MICROSCOPY (3.6 Å)