8DL8

Cryo-EM structure of human ferroportin/slc40 bound to Co2+ in nanodisc

Summary for 8DL8

• Entry DOI: 10.2210/pdb8dl8/pdb
• Related: 8DL7
• EMDB information: 27499
• Descriptor: Solute carrier family 40 member 1, 11F9 light-chain, 11F9 heavy-chain, ... (5 entities in total)
• Functional Keywords: slc40, fpn, ferroportin, iron, transporter, cobalt, human, nanodisc, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 112813.41

Authors

Shen, J.,Wilbon, A.S.,Pan, Y.,Zhou, M. (deposition date: 2022-07-07, release date: 2022-12-07, Last modification date: 2023-02-01)

• Primary citation: Wilbon, A.S.,Shen, J.,Ruchala, P.,Zhou, M.,Pan, Y.; Structural basis of ferroportin inhibition by minihepcidin PR73.; Plos Biol., 21:e3001936-e3001936, 2023; PubMed: 36649314; DOI: 10.1371/journal.pbio.3001936

Experimental method

ELECTRON MICROSCOPY (3 Å)