8D4R

Crystal Structure of Mosaic HIV-1 Envelope (MosM3.2) in Complex with antibodies PGT124 and 35O22 at 3.8 Angstrom

Summary for 8D4R

• Entry DOI: 10.2210/pdb8d4r/pdb
• Descriptor: Envelope glycoprotein gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: hiv-1 envelope protein, b cell targeting, mosaic design, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 161921.15

Authors

Xian, Y.,Wilson, I.A. (deposition date: 2022-06-02, release date: 2023-12-13, Last modification date: 2024-05-15)

• Primary citation: Xian, Y.,Wilson, I.A.; The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.81 Å)