8C7H

Cryo-EM Map of the latTGF-beta 28G11 Fab complex

Summary for 8C7H

Entry DOI	10.2210/pdb8c7h/pdb
EMDB information	16460
Descriptor	Transforming growth factor beta-1, Transforming growth factor beta activator LRRC32, 28G11 Fab heavy chain, ... (6 entities in total)
Functional Keywords	fab-complex, garp, lat-tgf-beta, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	7
Total formula weight	197421.50
Authors	Ebenhoch, R.,Nar, H. (deposition date: 2023-01-16, release date: 2023-03-01, Last modification date: 2023-03-29)
Primary citation	Igney, F.H.,Ebenhoch, R.,Schiele, F.,Nar, H. Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7:200-212, 2023 Cited by PubMed: 36928178 DOI: 10.4049/immunohorizons.2200072 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation