8C62
Crystal structure of cisplatin/B-DNA adduct
Summary for 8C62
Entry DOI | 10.2210/pdb8c62/pdb |
Related | 8C63 8C64 |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), PLATINUM (II) ION (3 entities in total) |
Functional Keywords | duplex, b-dna, cisplatin, anticancer agent, metallodrug, dna |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 8107.10 |
Authors | Troisi, R.,Tito, G.,Ferraro, G.,Sica, F.,Merlino, A. (deposition date: 2023-01-11, release date: 2024-01-31, Last modification date: 2024-02-28) |
Primary citation | Troisi, R.,Tito, G.,Ferraro, G.,Sica, F.,Massai, L.,Geri, A.,Cirri, D.,Messori, L.,Merlino, A. On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer. Dalton Trans, 53:3476-3483, 2024 Cited by PubMed: 38270175DOI: 10.1039/d3dt04302a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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