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8OO3
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BU of 8oo3 by Molmil
X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 5 days soaking
Descriptor: AMMONIA, Angiogenin, D(-)-TARTARIC ACID, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2023-04-04
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.
Dalton Trans, 52, 2023
8OO4
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BU of 8oo4 by Molmil
X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 1 month soaking
Descriptor: AMMONIA, Angiogenin, PLATINUM (II) ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2023-04-04
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.
Dalton Trans, 52, 2023
7BD7
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BU of 7bd7 by Molmil
X-ray structure of Arsenoplatin-1-encapsulated horse spleen ferritin
Descriptor: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2020-12-21
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Arsenoplatin-Ferritin Nanocage: Structure and Cytotoxicity.
Int J Mol Sci, 22, 2021
6ZS8
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BU of 6zs8 by Molmil
X-ray structure of the adduct formed upon treating lysozyme with an aged solution of arsenoplatin-1
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Lysozyme, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2020-07-15
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:The first step of arsenoplatin-1 aggregation in solution unveiled by solving the crystal structure of its protein adduct.
Dalton Trans, 50, 2021
6Y3D
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BU of 6y3d by Molmil
X-ray structure of thermophilic C-phycocyanin from Galdiera phlegrea
Descriptor: ACETATE ION, C-phycocyanin alpha chain, C-phycocyanin beta chain, ...
Authors:Ferraro, G, Lucignano, R, Marseglia, A, Merlino, A.
Deposit date:2020-02-18
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of C-phycocyanin from Galdieria phlegrea: Determinants of thermostability and comparison with a C-phycocyanin in the entire phycobilisome.
Biochim Biophys Acta Bioenerg, 1861, 2020
7P8R
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BU of 7p8r by Molmil
X-ray structure of the adduct of a vanadium picolinate complex with RNase A at pH 5.1
Descriptor: Ribonuclease pancreatic, SULFATE ION, hydroxy(oxo)bis(pyridine-2-carboxylato-kappa~2~N,O)vanadium(3+)
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-07-23
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Spectroscopic/Computational Characterization and the X-ray Structure of the Adduct of the V IV O-Picolinato Complex with RNase A.
Inorg.Chem., 60, 2021
5IX6
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BU of 5ix6 by Molmil
X-ray structure of Auoxo3-encapsulated horse spleen apoferritin
Descriptor: CADMIUM ION, Ferritin light chain, GOLD ION, ...
Authors:Ferraro, G, Pontillo, N, Merlino, A.
Deposit date:2016-03-23
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Gold-based drug encapsulation within a ferritin nanocage: X-ray structure and biological evaluation as a potential anticancer agent of the Auoxo3-loaded protein.
Chem.Commun.(Camb.), 52, 2016
5JVX
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BU of 5jvx by Molmil
X-ray structure of the adduct formed in the reaction between thaumatin and a gold carbene compound
Descriptor: (1-butyl-3-methyl-1,3-dihydro-2H-imidazol-2-ylidene)(chloro)gold, CHLORIDE ION, L(+)-TARTARIC ACID, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-05-11
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:First Crystal Structure for a Gold Carbene-Protein Adduct.
Bioconjug.Chem., 27, 2016
5N27
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BU of 5n27 by Molmil
X-ray structure of human heavy chain ferritin (apo form)
Descriptor: CHLORIDE ION, Ferritin heavy chain, MAGNESIUM ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-02-07
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Cisplatin Binding Sites in Human H-Chain Ferritin.
Inorg Chem, 56, 2017
6SET
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BU of 6set by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 3 days exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEU
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BU of 6seu by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 21h exposure of protein crystals to compound 2
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEW
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BU of 6sew by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 24h exposure of protein crystals to compound 2
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEX
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BU of 6sex by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 21h exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEZ
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BU of 6sez by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 24h exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
5N26
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BU of 5n26 by Molmil
X-ray structure of human heavy chain ferritin in complex with cisplatin
Descriptor: CHLORIDE ION, Cisplatin, Ferritin heavy chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-02-07
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Cisplatin Binding Sites in Human H-Chain Ferritin.
Inorg Chem, 56, 2017
7QWH
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BU of 7qwh by Molmil
X-ray structure of the adduct formed upon reaction of a vanadium hydroxyquinoline complex with RNase A
Descriptor: 2,2-bis($l^{1}-oxidanyl)-3-oxa-1$l^{4}-aza-2$l^{4}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaene, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2022-01-25
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Interaction of VIVO-8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization
Inorg Chem Front, 2023
6QEA
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BU of 6qea by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Descriptor: DIMETHYL SULFOXIDE, Lysozyme C, NITRATE ION, ...
Authors:Merlino, A, Ferraro, G.
Deposit date:2019-01-07
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
8B7L
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BU of 8b7l by Molmil
X-ray structure of Auranofin-horse spleen ferritin
Descriptor: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-09-30
Release date:2022-12-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Evaluation of Auranofin Loading within Ferritin Nanocages.
Int J Mol Sci, 23, 2022
8B7O
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BU of 8b7o by Molmil
X-ray structure of Auranofin-human H-chain ferritin
Descriptor: CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-09-30
Release date:2022-12-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Evaluation of Auranofin Loading within Ferritin Nanocages.
Int J Mol Sci, 23, 2022
8OMT
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BU of 8omt by Molmil
X-ray structure of lysozyme obtained upon reaction with [VIVO(empp)2] (Structure C)
Descriptor: 1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)V(IV)O4, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lysozyme C, ...
Authors:Paolillo, M, Merlino, A, Ferraro, G.
Deposit date:2023-03-31
Release date:2023-06-07
Method:X-RAY DIFFRACTION (1.097 Å)
Cite:Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Inorg.Chem., 62, 2023
8OMS
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BU of 8oms by Molmil
X-ray structure of lysozyme obtained upon reaction with [VIVO(empp)2] (Structure B)
Descriptor: Lysozyme C, bis-[(1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)]-V(IV)O2
Authors:Paolillo, M, Ferraro, G, Merlino, A.
Deposit date:2023-03-31
Release date:2023-06-07
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Inorg.Chem., 62, 2023
7NPM
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BU of 7npm by Molmil
X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
Descriptor: Angiogenin, D(-)-TARTARIC ACID, PLATINUM (II) ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-02-27
Release date:2022-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.
J.Inorg.Biochem., 226, 2022
8OM8
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BU of 8om8 by Molmil
X-ray structure of lysozyme obtained upon reaction with [VIVO(empp)2] (Structure A)
Descriptor: 1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)V(IV)O4, ACETATE ION, CHLORIDE ION, ...
Authors:Paolillo, M, Ferraro, G, Merlino, A.
Deposit date:2023-03-31
Release date:2023-06-07
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Inorg.Chem., 62, 2023
7ZU6
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BU of 7zu6 by Molmil
Polyoxidovanadate interaction with proteins: crystal structure of lysozyme bound to tetra-vanadate ion (structure 1)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CYCLO-TETRAMETAVANADATE, Lysozyme, ...
Authors:Tito, G, Merlino, A, Ferraro, G.
Deposit date:2022-05-11
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.183 Å)
Cite:Stabilization and Binding of [V 4 O 12 ] 4- and Unprecedented [V 20 O 54 (NO 3 )] n- to Lysozyme upon Loss of Ligands and Oxidation of the Potential Drug V IV O(acetylacetonato) 2.
Angew.Chem.Int.Ed.Engl., 62, 2023
8AJ4
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BU of 8aj4 by Molmil
X-ray structure of lysozyme obtained upon reaction with [VIVO(malt)2] (Structure A')
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8,8-bis($l^{1}-oxidanyl)-2,2'-dimethyl-8,8'-spirobi[3$l^{4},7,9-trioxa-8$l^{6}-vanadabicyclo[4.3.0]nona-1(6),2,4-triene], Lysozyme, ...
Authors:Paolillo, M, Merlino, A, Ferraro, G.
Deposit date:2022-07-27
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme.
Inorg.Chem., 61, 2022

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