8C3R

Crystal structure of DYRK1A in complex with gossypin

Summary for 8C3R

Entry DOI	10.2210/pdb8c3r/pdb
Descriptor	Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Gossypin, ACETATE ION, ... (4 entities in total)
Functional Keywords	kinase, diabetes, kinase inhibitor, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	87558.08
Authors	Grygier, P.,Pustelny, K.,Dubin, G.,Czarna, A. (deposition date: 2022-12-28, release date: 2024-01-10)
Primary citation	Grygier, P.,Pustelny, K.,Dubin, G.,Czarna, A. Crystal structure of DYRK1A in complex with gossypin To Be Published,
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation