8C3R
Crystal structure of DYRK1A in complex with gossypin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 370 | 43180.6 | 2 | UniProt (Q13627) Pfam (PF00069) In PDB | Homo sapiens (human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB |
2 | A, B | Gossypin | non-polymer | 480.4 | 2 | Chemie (R7O) | |||
3 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
4 | water | water | 18.0 | 420 | Chemie (HOH) |
Sequence modifications
A, B: 126 - 489 (UniProt: Q13627)
PDB | External Database | Details |
---|---|---|
His 490 | - | expression tag |
His 491 | - | expression tag |
His 492 | - | expression tag |
His 493 | - | expression tag |
His 494 | - | expression tag |
His 495 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 86361.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1196.9 | |
All* | Total formula weight | 87558.1 |