8C03
Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation
Summary for 8C03
| Entry DOI | 10.2210/pdb8c03/pdb |
| EMDB information | 16354 |
| Descriptor | Solute carrier family 40 member 1, 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide (2 entities in total) |
| Functional Keywords | iron, inhibitor, slc40, transporter, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 63945.28 |
| Authors | Lehmann, E.F.,Liziczai, M.,Drozdzyk, K.,Dutzler, R.,Manatschal, C. (deposition date: 2022-12-15, release date: 2023-03-22, Last modification date: 2023-05-24) |
| Primary citation | Lehmann, E.F.,Liziczai, M.,Drozdzyk, K.,Altermatt, P.,Langini, C.,Manolova, V.,Sundstrom, H.,Durrenberger, F.,Dutzler, R.,Manatschal, C. Structures of ferroportin in complex with its specific inhibitor vamifeport. Elife, 12:-, 2023 Cited by PubMed: 36943194DOI: 10.7554/eLife.83053 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.89 Å) |
Structure validation
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