8C03
Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Solute carrier family 40 member 1 | polymer | 580 | 63536.8 | 1 | UniProt (Q9NP59) Pfam (PF06963) In PDB | Homo sapiens (human) | Ferroportin-1,Iron-regulated transporter 1 |
2 | A | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide | non-polymer | 408.4 | 1 | Chemie (SZU) |
Sequence modifications
A: 2 - 571 (UniProt: Q9NP59)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ser 1 | - | expression tag |
Ala 572 | - | expression tag |
Leu 573 | - | expression tag |
Glu 574 | - | expression tag |
Val 575 | - | expression tag |
Leu 576 | - | expression tag |
Phe 577 | - | expression tag |
Gln 578 | - | expression tag |
Gly 579 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63536.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 408.4 | |
All* | Total formula weight | 63945.3 |