8BR9
Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22
Summary for 8BR9
| Entry DOI | 10.2210/pdb8br9/pdb |
| Descriptor | DNA repair and recombination protein RadA, Breast cancer type 2 susceptibility protein, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | stapled peptide, rad51, brca2, brc repeat, recombination |
| Biological source | Pyrococcus furiosus More |
| Total number of polymer chains | 2 |
| Total formula weight | 30105.97 |
| Authors | Pantelejevs, T.,Hyvonen, M. (deposition date: 2022-11-22, release date: 2023-03-08, Last modification date: 2024-02-07) |
| Primary citation | Pantelejevs, T.,Zuazua-Villar, P.,Koczy, O.,Counsell, A.J.,Walsh, S.J.,Robertson, N.S.,Spring, D.R.,Downs, J.A.,Hyvonen, M. A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chem Sci, 14:13915-13923, 2023 Cited by PubMed: 38075664DOI: 10.1039/d3sc03331g PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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