8B2C

Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative

This is a non-PDB format compatible entry.

Summary for 8B2C

• Entry DOI: 10.2210/pdb8b2c/pdb
• Descriptor: 3-dehydroquinate dehydratase, (1~{S},2~{R},4~{R},5~{S},6~{S})-2,4,5-trihydroxy-7-oxabicyclo[4.1.0]heptane-2-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: chorismate biosynthetic process, 3-dehydroquinase, lyase
• Biological source: Salmonella enterica subsp. enterica serovar Typhi
• Total number of polymer chains: 1
• Total formula weight: 28301.57

Authors

Otero, J.M.,Rodriguez, A.,Maneiro, M.,Lence, E.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2022-09-13, release date: 2023-02-15, Last modification date: 2024-02-07)

• Primary citation: Rodriguez, A.,Maneiro, M.,Lence, E.,Otero, J.M.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C.; Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight.; Front Mol Biosci, 10:1111598-1111598, 2023; PubMed: 36762206; DOI: 10.3389/fmolb.2023.1111598

Experimental method

X-RAY DIFFRACTION (1.55 Å)