8AS6

Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK]

Summary for 8AS6

• Entry DOI: 10.2210/pdb8as6/pdb
• Related: 8AS7 8ASB 8ASD
• EMDB information: 15607
• Descriptor: RNA-dependent RNA-polymerase L protein, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3') (2 entities in total)
• Functional Keywords: sftsv rna-dependent rna polymerase, viral rna, viral protein
• Biological source: SFTS virus AH12; More
• Total number of polymer chains: 2
• Total formula weight: 242150.48

Authors

Williams, H.M.,Thorkelsson, S.R.,Vogel, D.,Milewski, M.,Busch, C.,Cusack, S.,Grunewald, K.,Quemin, E.R.J.,Rosenthal, M. (deposition date: 2022-08-18, release date: 2023-01-18, Last modification date: 2023-03-01)

• Primary citation: Williams, H.M.,Thorkelsson, S.R.,Vogel, D.,Milewski, M.,Busch, C.,Cusack, S.,Grunewald, K.,Quemin, E.R.J.,Rosenthal, M.; Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.; Nucleic Acids Res., 51:1424-1442, 2023; PubMed: 36651274; DOI: 10.1093/nar/gkac1249

Experimental method

ELECTRON MICROSCOPY (3.4 Å)