7ZXG

Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8

Summary for 7ZXG

• Entry DOI: 10.2210/pdb7zxg/pdb
• Descriptor: Gametocyte surface protein P45/48, 10D8 heavy chain, 10D8 light chain, ... (7 entities in total)
• Functional Keywords: pfs48/45, malaria, transmission-blocking, plasmodium falciparum, gamete, antibody, cell adhesion
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 6
• Total formula weight: 257458.30

Authors

Ko, K.T.,Lennartz, F.L.,Higgins, M.K. (deposition date: 2022-05-20, release date: 2022-06-22, Last modification date: 2024-01-31)

• Primary citation: Ko, K.T.,Lennartz, F.,Mekhaiel, D.,Guloglu, B.,Marini, A.,Deuker, D.J.,Long, C.A.,Jore, M.M.,Miura, K.,Biswas, S.,Higgins, M.K.; Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.; Nat Commun, 13:5603-5603, 2022; PubMed: 36153317; DOI: 10.1038/s41467-022-33379-6

Experimental method

X-RAY DIFFRACTION (4.2 Å)