7VZQ

The structure of GdmN V24Y/G157A/R158A/G188R mutant in complex with carbamoyl adenylate intermediate

Summary for 7VZQ

• Entry DOI: 10.2210/pdb7vzq/pdb
• Descriptor: GdmN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, FE (III) ION, ... (8 entities in total)
• Functional Keywords: homodimer, carbamoyltransferase, ansamycins antibiotics, transferase
• Biological source: Streptomyces hygroscopicus
• Total number of polymer chains: 2
• Total formula weight: 155467.74

Authors

Wei, J.,Zheng, J.,Zhou, J.,Kang, Q.,Bai, L. (deposition date: 2021-11-16, release date: 2022-11-16, Last modification date: 2023-11-29)

• Primary citation: Wei, J.,Zhang, X.,Zhou, Y.,Cheng, X.,Lin, Z.,Tang, M.,Zheng, J.,Wang, B.,Kang, Q.,Bai, L.; Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.; Nat Commun, 13:6617-6617, 2022; PubMed: 36329057; DOI: 10.1038/s41467-022-34387-2

Experimental method

X-RAY DIFFRACTION (2.1 Å)