7VYX

Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex

Summary for 7VYX

• Entry DOI: 10.2210/pdb7vyx/pdb
• Descriptor: Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, sgRNA, Target DNA strand, ... (5 entities in total)
• Functional Keywords: cas12c, cas12c1, crispr, rna binding protein-rna-dna complex, rna binding protein/rna/dna
• Biological source: Parasutterella muris; More
• Total number of polymer chains: 8
• Total formula weight: 421279.38

Authors

Zhang, B.,Lin, J.Y.,Perculija, V.,OuYang, S.Y. (deposition date: 2021-11-15, release date: 2022-11-02, Last modification date: 2023-06-14)

• Primary citation: Zhang, B.,Lin, J.,Perculija, V.,Li, Y.,Lu, Q.,Chen, J.,Ouyang, S.; Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system; Nucleic Acids Res., 50:11820-11833, 2022; DOI: 10.1093/nar/gkac987

Experimental method

X-RAY DIFFRACTION (3.2 Å)