7UGM

Crystal Structure of BG24-iGL CDR3mat Fab

Summary for 7UGM

Entry DOI	10.2210/pdb7ugm/pdb
Descriptor	BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain (3 entities in total)
Functional Keywords	fab, igg, bg24, anti-hiv antibody, bnab, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	46195.43
Authors	Dam, K.A.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2022-03-25, release date: 2022-11-09, Last modification date: 2023-10-18)
Primary citation	Dam, K.A.,Barnes, C.O.,Gristick, H.B.,Schoofs, T.,Gnanapragasam, P.N.P.,Nussenzweig, M.C.,Bjorkman, P.J. HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13:6123-6123, 2022 Cited by PubMed: 36253376 DOI: 10.1038/s41467-022-33860-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation