7TBL

Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC

This is a non-PDB format compatible entry.

Summary for 7TBL

• Entry DOI: 10.2210/pdb7tbl/pdb
• Related: 1XKS 3CQC 3FMO 4FHN 4I0O 4I79 4LIR 4XMM 5C2U 5C3L 5CWS 5HAX 5HAY 5HB0 5HB1 6B4F 7MNI 7MNL 7MVV 7MVZ 7MW1
• EMDB information: 14322
• Descriptor: NUP155, NUP98 R2, NUP205, ... (44 entities in total)
• Functional Keywords: nuclear pore complex, nucleocytoplasmic transport, alpha-helical solenoid, nuclear pore, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 141
• Total formula weight: 6611247.98

Authors

Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A. (deposition date: 2021-12-22, release date: 2022-06-22, Last modification date: 2022-06-29)

• Primary citation: Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A.; Architecture of the cytoplasmic face of the nuclear pore.; Science, 376:eabm9129-eabm9129, 2022; PubMed: 35679405; DOI: 10.1126/science.abm9129

Experimental method

ELECTRON MICROSCOPY (23 Å)