7SGF

Lassa virus glycoprotein construct (Josiah GPC-I53-50A) in complex with LAVA01 antibody

Summary for 7SGF

• Entry DOI: 10.2210/pdb7sgf/pdb
• EMDB information: 25107 25108 25109
• Descriptor: GPC-I53-50A, LAVA01 mAb - Heavy Chain, LAVA01 mAb - Light Chain, ... (9 entities in total)
• Functional Keywords: glycoprotein, lassa, josiah, vaccine design, nanoparticle, protein design, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa mammarenavirus; More
• Total number of polymer chains: 12
• Total formula weight: 543990.93

Authors

Antanasijevic, A.,Brouwer, P.J.M.,Ward, A.B. (deposition date: 2021-10-05, release date: 2022-10-12, Last modification date: 2022-12-28)

• Primary citation: Brouwer, P.J.M.,Antanasijevic, A.,Ronk, A.J.,Muller-Krauter, H.,Watanabe, Y.,Claireaux, M.,Perrett, H.R.,Bijl, T.P.L.,Grobben, M.,Umotoy, J.C.,Schriek, A.I.,Burger, J.A.,Tejjani, K.,Lloyd, N.M.,Steijaert, T.H.,van Haaren, M.M.,Sliepen, K.,de Taeye, S.W.,van Gils, M.J.,Crispin, M.,Strecker, T.,Bukreyev, A.,Ward, A.B.,Sanders, R.W.; Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.; Cell Host Microbe, 30:1759-, 2022; PubMed: 36400021; DOI: 10.1016/j.chom.2022.10.018

Experimental method

ELECTRON MICROSCOPY (4.41 Å)