7SGF
Lassa virus glycoprotein construct (Josiah GPC-I53-50A) in complex with LAVA01 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, a, B, b, C... | GPC-I53-50A | polymer | 665 | 73845.6 | 6 | UniProt (Q6GWS0) Pfam (PF00798) UniProt (by SIFTS) (P08669) In PDB | Lassa mammarenavirus | |
| 2 | H, J, M | LAVA01 mAb - Heavy Chain | polymer | 142 | 15459.2 | 3 | Oryctolagus cuniculus (Rabbit) | ||
| 3 | L, K, N | LAVA01 mAb - Light Chain | polymer | 120 | 12490.6 | 3 | Oryctolagus cuniculus (Rabbit) | ||
| 4 | d, e, i, D, m... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 9 | In PDB GlyTouCan (G15407YE) | |||
| 5 | X, f, h, j, E... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 6 | g, F, U | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 7 | Y, k, P | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
| 8 | Z, l, Q | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 9 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, a, B, b, C, c: 1 - 423 (UniProt: Q6GWS0)
A, a, B, b, C, c: 424 - 665 (PDB: 7SGF)
| PDB | External Database | Details |
|---|---|---|
| Cys 207 | Arg 207 | conflict |
| Arg 258 | Leu 258 | conflict |
| Arg 259 | Leu 259 | conflict |
| Pro 329 | Glu 329 | conflict |
| Cys 360 | Gly 360 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 526923.1 | |
| Branched | Number of molecules | 27 |
| Total formula weight | 15740.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 543990.9 |
