7S0P

Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine

This is a non-PDB format compatible entry.

Summary for 7S0P

• Entry DOI: 10.2210/pdb7s0p/pdb
• Descriptor: Coagulation factor VIII, PHOSPHOSERINE (3 entities in total)
• Functional Keywords: factor viii, lipid, hemostasis, lipid binding protein
• Biological source: Sus scrofa (Pig)
• Total number of polymer chains: 1
• Total formula weight: 17686.89

Authors

Peters, S.C.,Childers, K.C.,Wo, S.W.,Brison, C.M.,Swanson, C.D.,Spiegel, P.C. (deposition date: 2021-08-30, release date: 2021-10-27, Last modification date: 2023-10-25)

• Primary citation: Peters, S.C.,Childers, K.C.,Mitchell, C.E.,Avery, N.G.,Reese Jr., S.S.,Mitchell, C.,Wo, S.W.,Swanson, C.D.,Brison, C.M.,Spiegel Jr., P.C.; Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.; Front Mol Biosci, 9:1040106-1040106, 2022; PubMed: 36387287; DOI: 10.3389/fmolb.2022.1040106

Experimental method

X-RAY DIFFRACTION (1.3 Å)