7RWA
AP2 bound to heparin and Tgn38 tyrosine cargo peptide
Summary for 7RWA
| Entry DOI | 10.2210/pdb7rwa/pdb |
| EMDB information | 24710 24711 24712 |
| Descriptor | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... (5 entities in total) |
| Functional Keywords | ap2, clathrin vesicle, endocytosis, lipid-binding, adaptor, membrane, transport, cargo |
| Biological source | Mus musculus (Mouse) More |
| Total number of polymer chains | 10 |
| Total formula weight | 412203.99 |
| Authors | Baker, R.W.,Hollopeter, G.,Partlow, E.A. (deposition date: 2021-08-19, release date: 2022-03-30, Last modification date: 2022-04-27) |
| Primary citation | Partlow, E.A.,Cannon, K.S.,Hollopeter, G.,Baker, R.W. Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29:339-347, 2022 Cited by PubMed: 35347313DOI: 10.1038/s41594-022-00749-z PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
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