Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7R8U

LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis

This is a non-PDB format compatible entry.
Summary for 7R8U
Entry DOI10.2210/pdb7r8u/pdb
DescriptorOxidized low-density lipoprotein receptor 1, Antigen binding fragment, Vh and Ch1, Antibody light chain, kappa, ... (5 entities in total)
Functional Keywordslow density lipoprotein receptor antibody complex lox-1 scavenger receptor atherogenesis-atherosclerosis macrophage cardiovascular disease, signaling protein-immune system complex, signaling protein/immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight77981.45
Authors
Oganesyan, V.,van Dyk, N. (deposition date: 2021-06-27, release date: 2022-06-01, Last modification date: 2023-11-29)
Primary citationOngstad, E.L.,Gaddipati, R.,Belkhodja, M.,van Dyk, N.,Levy, S.,Sagar, D.,Cariuk, P.,Wolny, M.,Hanna, R.N.,Borrok, M.J.,Buchanan, A.,Oganesyan, V.,Gupta, R.
Structural and functional studies of a monoclonal antibody blocking LOX-1
Commun Med, 2023
Experimental method
X-RAY DIFFRACTION (1.901 Å)
Structure validation

219869

PDB entries from 2024-05-15

PDB statisticsPDBj update infoContact PDBjnumon