7QSR

CryoEM structure of the Ectodomain of Human PLA2R

This is a non-PDB format compatible entry.

Summary for 7QSR

• Entry DOI: 10.2210/pdb7qsr/pdb
• EMDB information: 14077
• Descriptor: Secretory phospholipase A2 receptor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: receptor, ectodomain, glycoprotein, nephrology, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 163949.62

Authors

Briggs, D.C.,Lockhart-Cairns, M.P.,Baldock, C. (deposition date: 2022-01-14, release date: 2022-07-20, Last modification date: 2022-08-03)

• Primary citation: Fresquet, M.,Lockhart-Cairns, M.P.,Rhoden, S.J.,Jowitt, T.A.,Briggs, D.C.,Baldock, C.,Brenchley, P.E.,Lennon, R.; Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.; Proc.Natl.Acad.Sci.USA, 119:e2202209119-e2202209119, 2022; PubMed: 35858348; DOI: 10.1073/pnas.2202209119

Experimental method

ELECTRON MICROSCOPY (3.4 Å)