7QOX

Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes

Summary for 7QOX

• Entry DOI: 10.2210/pdb7qox/pdb
• Descriptor: Plasma kallikrein heavy chain, Kininogen-1 light chain, GLYCEROL, ... (9 entities in total)
• Functional Keywords: plasma kallikrein (pk), high molecular weight kininogen (hk), factor xii (fxii), factor xi (fxi), factor ix (fix), bradykinin (bk), blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 91685.97

Authors

Li, C.,Awital, B.,Wong, S.,Dreveny, I.,Meijers, J.,Emsley, J. (deposition date: 2021-12-29, release date: 2023-01-18, Last modification date: 2024-01-31)

• Primary citation: Li, C.,Voos, K.M.,Pathak, M.,Hall, G.,McCrae, K.R.,Dreveny, I.,Li, R.,Emsley, J.; Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.; J Thromb Haemost, 17:759-770, 2019; PubMed: 30801944; DOI: 10.1111/jth.14418

Experimental method

X-RAY DIFFRACTION (2.32 Å)