7PQQ
Structure of thermostabilised human NTCP in complex with Megabody 91
Summary for 7PQQ
| Entry DOI | 10.2210/pdb7pqq/pdb |
| EMDB information | 13596 |
| Descriptor | Sodium/bile acid cotransporter, Anti-RON nanobody,Megabody 91,Glucosidase YgjK (2 entities in total) |
| Functional Keywords | bile acid transporter, membrane protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 138235.42 |
| Authors | Goutam, K.,Reyes, N. (deposition date: 2021-09-18, release date: 2022-05-18, Last modification date: 2022-07-06) |
| Primary citation | Goutam, K.,Ielasi, F.S.,Pardon, E.,Steyaert, J.,Reyes, N. Structural basis of sodium-dependent bile salt uptake into the liver. Nature, 606:1015-1020, 2022 Cited by PubMed: 35545671DOI: 10.1038/s41586-022-04723-z PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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