7PI2
PfCyRPA bound to monoclonal antibody Cy.003 Fab fragment
Summary for 7PI2
Entry DOI | 10.2210/pdb7pi2/pdb |
Descriptor | Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, Monoclonal antibody Cy.003 light chain (3 entities in total) |
Functional Keywords | malaria, plasmodium falciparum, monoclonal antibody, vaccine, immune system |
Biological source | Plasmodium falciparum (isolate 3D7) More |
Total number of polymer chains | 12 |
Total formula weight | 345933.13 |
Authors | Ragotte, R.J.,Higgins, M.K. (deposition date: 2021-08-19, release date: 2022-02-09, Last modification date: 2024-01-31) |
Primary citation | Ragotte, R.J.,Pulido, D.,Lias, A.M.,Quinkert, D.,Alanine, D.G.W.,Jamwal, A.,Davies, H.,Nacer, A.,Lowe, E.D.,Grime, G.W.,Illingworth, J.J.,Donat, R.F.,Garman, E.F.,Bowyer, P.W.,Higgins, M.K.,Draper, S.J. Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13:933-933, 2022 Cited by PubMed: 35177602DOI: 10.1038/s41467-022-28601-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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