7P8L

Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG

Summary for 7P8L

• Entry DOI: 10.2210/pdb7p8l/pdb
• Descriptor: N-glycosylase/DNA lyase, DNA (5'-D(*TP*TP*TP*(8OG)P*TP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), ... (5 entities in total)
• Functional Keywords: 8-oxoguanine dna glycosylase, pyrococcus abyssi, protein-dna complex, hydrolase
• Biological source: Pyrococcus abyssi (strain GE5 / Orsay); More
• Total number of polymer chains: 3
• Total formula weight: 33702.47

Authors

Coste, F.,Flament, D.,Castaing, B. (deposition date: 2021-07-23, release date: 2022-08-03, Last modification date: 2024-01-31)

• Primary citation: Franck, C.,Stephane, G.,Julien, C.,Virginie, G.,Martine, G.,Norbert, G.,Fabrice, C.,Didier, F.,Josef, S.M.,Bertrand, C.; Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.; Nucleic Acids Res., 50:11072-11092, 2022; PubMed: 36300625; DOI: 10.1093/nar/gkac932

Experimental method

X-RAY DIFFRACTION (1.25 Å)