7OTC

Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B

This is a non-PDB format compatible entry.

Summary for 7OTC

• Entry DOI: 10.2210/pdb7otc/pdb
• Related: 7UG7
• EMDB information: 13058 26486
• Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (59 entities in total)
• Functional Keywords: antibiotic, ribosome, translation
• Biological source: Escherichia coli BL21(DE3); More
• Total number of polymer chains: 52
• Total formula weight: 2188658.26

Authors

Wieland, M.,Koller, T.O.,Wilson, D.N. (deposition date: 2021-06-10, release date: 2022-05-11, Last modification date: 2024-04-24)

• Primary citation: Wieland, M.,Holm, M.,Rundlet, E.J.,Morici, M.,Koller, T.O.,Maviza, T.P.,Pogorevc, D.,Osterman, I.A.,Muller, R.,Blanchard, S.C.,Wilson, D.N.; The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.; Proc.Natl.Acad.Sci.USA, 119:e2114214119-e2114214119, 2022; PubMed: 35500116; DOI: 10.1073/pnas.2114214119

Experimental method

ELECTRON MICROSCOPY (2.9 Å)