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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7OTC

Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a16S ribosomal RNApolymer1533497061.71GenBank (1758835854)Escherichia coli BL21(DE3)
2b30S ribosomal protein S2polymer22625200.01UniProt (A0A140NFK2)
Pfam (PF00318)
In PDB		Escherichia coli BL21(DE3)
3c30S ribosomal protein S3polymer20623078.81UniProt (A0A140N4K1)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Escherichia coli BL21(DE3)
4d30S ribosomal protein S4polymer20523383.01UniProt (A0A140N548)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Escherichia coli BL21(DE3)
5e30S ribosomal protein S5polymer15716532.11UniProt (A0A140N6Z9)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Escherichia coli BL21(DE3)
6f30S ribosomal protein S6polymer10612326.31UniProt (A0A140NGG7)
Pfam (PF01250)
In PDB		Escherichia coli BL21(DE3)
7g30S ribosomal protein S7polymer15617619.41UniProt (A0A140N6W8)
Pfam (PF00177)
In PDB		Escherichia coli BL21(DE3)
8h30S ribosomal protein S8polymer12914015.41UniProt (A0A140N537)
Pfam (PF00410)
In PDB		Escherichia coli BL21(DE3)
9i30S ribosomal protein S9polymer12714554.91UniProt (A0A140N2Z9)
Pfam (PF00380)
In PDB		Escherichia coli BL21(DE3)
10j30S ribosomal protein S10polymer9911325.11UniProt (A0A140N6Y5)
Pfam (PF00338)
In PDB		Escherichia coli BL21(DE3)
11k30S ribosomal protein S11polymer11712487.21UniProt (A0A140N7L9)
Pfam (PF00411)
In PDB		Escherichia coli BL21(DE3)
12l30S ribosomal protein S12polymer12313683.11UniProt (A0A140N4H3)
Pfam (PF00164)
In PDB		Escherichia coli BL21(DE3)
13m30S ribosomal protein S13polymer11512738.91UniProt (A0A140N5B4)
Pfam (PF00416)
In PDB		Escherichia coli BL21(DE3)
14n30S ribosomal protein S14polymer10111606.61UniProt (A0A140N7K8)
Pfam (PF00253)
In PDB		Escherichia coli BL21(DE3)
15o30S ribosomal protein S15polymer8810159.61UniProt (A0A140N811)
Pfam (PF00312)
In PDB		Escherichia coli BL21(DE3)
16p30S ribosomal protein S16polymer829207.61UniProt (A0A140N7D8)
Pfam (PF00886)
In PDB		Escherichia coli BL21(DE3)
17q30S ribosomal protein S17polymer809263.91UniProt (A0A140N6Z6)
Pfam (PF00366)
In PDB		Escherichia coli BL21(DE3)
18r30S ribosomal protein S18polymer677893.11UniProt (A0A140NGH1)
Pfam (PF01084)
In PDB		Escherichia coli BL21(DE3)
19s30S ribosomal protein S19polymer9210455.41UniProt (A0A140N528)
Pfam (PF00203)
In PDB		Escherichia coli BL21(DE3)
20t30S ribosomal protein S20polymer869577.31UniProt (A0A140NFU3)
Pfam (PF01649)
In PDB		Escherichia coli BL21(DE3)
21u30S ribosomal protein S21polymer708392.81UniProt (A0A140N8B4)
Pfam (PF01165)
In PDB		Escherichia coli BL21(DE3)
22A23S ribosomal RNApolymer2903941505.41Escherichia coli BL21(DE3)
23B5S ribosomal RNApolymer12038790.11GenBank (1845283434)Escherichia coli BL21(DE3)
24C50S ribosomal protein L2polymer27129663.21UniProt (A0A140N7J1)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Escherichia coli BL21(DE3)
25D50S ribosomal protein L3polymer20922277.51UniProt (A0A140N3G7)
Pfam (PF00297)
In PDB		Escherichia coli BL21(DE3)
26E50S ribosomal protein L4polymer20122121.61UniProt (A0A140N5K8)
Pfam (PF00573)
In PDB		Escherichia coli BL21(DE3)
27F50S ribosomal protein L5polymer17720073.21UniProt (A0A140N5A3)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Escherichia coli BL21(DE3)
28G50S ribosomal protein L6polymer17618801.61UniProt (A0A140N2T1)
Pfam (PF00347)
In PDB		Escherichia coli BL21(DE3)
29J50S ribosomal protein L13polymer14216050.61UniProt (A0A140N598)
Pfam (PF00572)
In PDB		Escherichia coli BL21(DE3)
30K50S ribosomal protein L14polymer12313565.11UniProt (A0A140N3H4)
Pfam (PF00238)
In PDB		Escherichia coli BL21(DE3)
31L50S ribosomal protein L15polymer14415008.51UniProt (A0A140N711)
Pfam (PF00828)
In PDB		Escherichia coli BL21(DE3)
32M50S ribosomal protein L16polymer13615327.31UniProt (A0A140N6Z2)
Pfam (PF00252)
In PDB		Escherichia coli BL21(DE3)
33N50S ribosomal protein L17polymer12013721.91UniProt (A0A140N4M0)
Pfam (PF01196)
In PDB		Escherichia coli BL21(DE3)
34O50S ribosomal protein L18polymer11612663.51UniProt (A0A140N4L0)
Pfam (PF00861)
In PDB		Escherichia coli BL21(DE3)
35P50S ribosomal protein L19polymer11413028.11UniProt (A0A140N6T7)
Pfam (PF01245)
In PDB		Escherichia coli BL21(DE3)
36Q50S ribosomal protein L20polymer11713396.81UniProt (A0A140NBS1)
Pfam (PF00453)
In PDB		Escherichia coli BL21(DE3)
37R50S ribosomal protein L21polymer10311586.41UniProt (A0A140N5D7)
Pfam (PF00829)
In PDB		Escherichia coli BL21(DE3)
38S50S ribosomal protein L22polymer11012253.41UniProt (A0A140N2S3)
Pfam (PF00237)
In PDB		Escherichia coli BL21(DE3)
39T50S ribosomal protein L23polymer9310546.51UniProt (C6EGE8)
Pfam (PF00276)
In PDB		Escherichia coli BL21(DE3)
40U50S ribosomal protein L24polymer10211078.91UniProt (A0A140N5L7)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Escherichia coli BL21(DE3)
41V50S ribosomal protein L25polymer9410713.51UniProt (A0A140N846)
Pfam (PF01386)
In PDB		Escherichia coli BL21(DE3)
42W50S ribosomal protein L27polymer849015.31UniProt (A0A140N340)
Pfam (PF01016)
In PDB		Escherichia coli BL21(DE3)
43X50S ribosomal protein L28polymer778896.41UniProt (A0A140N3L9)
Pfam (PF00830)
In PDB		Escherichia coli BL21(DE3)
44Y50S ribosomal protein L29polymer637286.51UniProt (A0A140N7F5)
Pfam (PF00831)
In PDB		Escherichia coli BL21(DE3)
45Z50S ribosomal protein L30polymer586423.61UniProt (A0A140N7G4)
Pfam (PF00327)
In PDB		Escherichia coli BL21(DE3)
46550S ribosomal protein L31polymer677613.81UniProt (A0A140SS71)
Pfam (PF01197)
In PDB		Escherichia coli BL21(DE3)
47050S ribosomal protein L32polymer566332.21UniProt (A0A140NAZ2)
Pfam (PF01783)
In PDB		Escherichia coli BL21(DE3)
48150S ribosomal protein L33polymer505814.81UniProt (A0A140N5Z7)
Pfam (PF00471)
In PDB		Escherichia coli BL21(DE3)
49250S ribosomal protein L34polymer465397.51UniProt (A0A140NHV0)
Pfam (PF00468)
In PDB		Escherichia coli BL21(DE3)
50350S ribosomal protein L35polymer647181.81UniProt (A0A140N9E3)
Pfam (PF01632)
In PDB		Escherichia coli BL21(DE3)
51450S ribosomal protein L36polymer384377.41UniProt (A0A140N5M6)
Pfam (PF00444)
In PDB		Escherichia coli BL21(DE3)
52wElongation factor Gpolymer70477571.01UniProt (A0A140N7C7)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF14492)
Pfam (PF03764)
Pfam (PF00679)
In PDB		Escherichia coli BL21(DE3)EF-G
53a, A, B, n, C...MAGNESIUM IONnon-polymer24.3292Chemie (MG)
54AADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
55A1,4-DIAMINOBUTANEnon-polymer88.28Chemie (PUT)
56ASPERMIDINEnon-polymer145.22Chemie (SPD)
575, 4ZINC IONnon-polymer65.42Chemie (ZN)
58wGUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
59wArgyrin Bnon-polymer838.91Chemie (1I7)
Sequence modifications
e: 10 - 166 (UniProt: A0A140N6Z9)
PDBExternal DatabaseDetails
Glu 151Ala 151conflict
g: 2 - 156 (UniProt: A0A140N6W8)
PDBExternal DatabaseDetails
Leu 157-expression tag
n: 2 - 101 (UniProt: A0A140N7K8)
PDBExternal DatabaseDetails
Met 1-initiating methionine
L: 1 - 144 (UniProt: A0A140N711)
PDBExternal DatabaseDetails
Ile 77Val 77conflict
w: 2 - 704 (UniProt: A0A140N7C7)
PDBExternal DatabaseDetails
Ser 1-expression tag
Thr 237Tyr 237variant
Asp 258Asn 258variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains52
Total formula weight2178645.4
Non-Polymers*Number of molecules307
Total formula weight10012.9
All*Total formula weight2188658.3
*Water molecules are not included.

219869

PDB entries from 2024-05-15

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