7O56
X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods
Summary for 7O56
Entry DOI | 10.2210/pdb7o56/pdb |
Descriptor | Interferon regulatory factor 4, DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP*GP*AP*AP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP*TP*CP*TP*TP*TP*TP*AP*T)-3') (3 entities in total) |
Functional Keywords | interferon regulatory factors, transcription regulation, protein-dna interaction, transcription, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 61799.83 |
Authors | El Omari, K.,Agnarelli, A.,Duman, R.,Wagner, A.,Mancini, E.J. (deposition date: 2021-04-07, release date: 2021-05-12, Last modification date: 2021-10-13) |
Primary citation | Agnarelli, A.,El Omari, K.,Duman, R.,Wagner, A.,Mancini, E.J. Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4. Acta Crystallogr.,Sect.F, 77:202-207, 2021 Cited by PubMed: 34196610DOI: 10.1107/S2053230X21006506 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report