7O56

X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00601
Number of Residues	34
Details	IRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagkqdynreeDaaLFKaWA

Chain	Residue	Details
A	TRP42-ALA75

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	324
Details	DNA_BIND: IRF tryptophan pentad repeat => ECO:0000255|PROSITE-ProRule:PRU00840

Chain	Residue	Details
A	ASN21-PRO129
B	ASN21-PRO129
C	ASN21-PRO129

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