7MM1

PTP1B in complex with TCS401 by Native S-SAD at Room Temperature

Summary for 7MM1

Entry DOI	10.2210/pdb7mm1/pdb
Related	7L84 7LVC
Descriptor	Tyrosine-protein phosphatase non-receptor type 1, 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	protein tyrosine phosphatase 1b, hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	37860.11
Authors	Greisman, J.B.,Dalton, K.M.,Hekstra, D.R. (deposition date: 2021-04-29, release date: 2021-05-12, Last modification date: 2022-08-17)
Primary citation	Greisman, J.B.,Dalton, K.M.,Sheehan, C.J.,Klureza, M.A.,Kurinov, I.,Hekstra, D.R. Native SAD phasing at room temperature. Acta Crystallogr D Struct Biol, 78:986-996, 2022 Cited by PubMed: 35916223 DOI: 10.1107/S2059798322006799 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation