7MFP

crystal structure of the L136 aminotransferase K185A from acanthamoeba polyphaga mimivirus in the presence of the UDP-viosamine external aldimine

Summary for 7MFP

• Entry DOI: 10.2210/pdb7mfp/pdb
• Related: 7mfo
• Descriptor: L136 aminotransferase, (2R,3R,4S,5S,6R)-3,4-dihydroxy-5-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyloxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name), CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: mimivirus, aminotransferase, viosamine, transferase
• Biological source: Acanthamoeba polyphaga mimivirus (APMV)
• Total number of polymer chains: 4
• Total formula weight: 164738.40

Authors

Seltzner, C.A.,Thoden, J.B.,Holden, H.M. (deposition date: 2021-04-10, release date: 2021-04-28, Last modification date: 2023-10-18)

• Primary citation: Seltzner, C.A.,Ferek, J.D.,Thoden, J.B.,Holden, H.M.; Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus.; Protein Sci., 30:1882-1894, 2021; PubMed: 34076307; DOI: 10.1002/pro.4139

Experimental method

X-RAY DIFFRACTION (1.85 Å)