7MDF

Full-length S95A ClbP bound to N-acyl-D-asparagine analog

Summary for 7MDF

Entry DOI	10.2210/pdb7mdf/pdb
Related	7MDC 7MDE 7UL6
Descriptor	Beta-lactamase, DIMETHYL SULFOXIDE, methyl N~2~-[4-(4-bromophenyl)butanoyl]-D-asparaginyl-L-alaninate, ... (10 entities in total)
Functional Keywords	colibactin peptidase, s12 peptidase, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Escherichia coli CFT073
Total number of polymer chains	1
Total formula weight	58040.08
Authors	Velilla, J.A.,Volpe, M.R.,Gaudet, R. (deposition date: 2021-04-04, release date: 2022-09-28, Last modification date: 2023-12-13)
Primary citation	Velilla, J.A.,Volpe, M.R.,Kenney, G.E.,Walsh Jr., R.M.,Balskus, E.P.,Gaudet, R. Structural basis of colibactin activation by the ClbP peptidase. Nat.Chem.Biol., 19:151-158, 2023 Cited by PubMed: 36253550 DOI: 10.1038/s41589-022-01142-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation