7MDC

Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid

Summary for 7MDC

Entry DOI	10.2210/pdb7mdc/pdb
Related	7MDE 7MDF 7UL6
Descriptor	Beta-lactamase, NONAETHYLENE GLYCOL, DIMETHYL SULFOXIDE, ... (8 entities in total)
Functional Keywords	colibactin peptidase, s12 peptidase, boronic acid inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	56711.25
Authors	Velilla, J.A.,Volpe, M.R.,Gaudet, R. (deposition date: 2021-04-03, release date: 2022-09-28, Last modification date: 2023-10-25)
Primary citation	Volpe, M.R.,Velilla, J.A.,Daniel-Ivad, M.,Yao, J.J.,Stornetta, A.,Villalta, P.W.,Huang, H.C.,Bachovchin, D.A.,Balbo, S.,Gaudet, R.,Balskus, E.P. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat.Chem.Biol., 19:159-167, 2023 Cited by PubMed: 36253549 DOI: 10.1038/s41589-022-01147-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation