7M15

crystal structure of cj1430 in the presence of GDP-D-glycero-L-gluco-heptose, a GDP-D-glycero-4-keto-D-lyxo-heptose-3,5-epimerase from campylobacter jejuni

Summary for 7M15

• Entry DOI: 10.2210/pdb7m15/pdb
• Descriptor: GDP-D-glycero-L-gluco-heptose, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4R,5R,6S)-6-[(1R)-1,2-dihydroxyethyl]-3,4,5-trihydroxyoxan-2-yl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: 3, 5-epimerase, capsular polysaccharide, isomerase
• Biological source: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
• Total number of polymer chains: 6
• Total formula weight: 132314.46

Authors

Girardi, N.M.,Thoden, J.B.,Raushel, F.M.,Holden, H.M. (deposition date: 2021-03-12, release date: 2021-03-24, Last modification date: 2023-10-18)

• Primary citation: Huddleston, J.P.,Anderson, T.K.,Girardi, N.M.,Thoden, J.B.,Taylor, Z.,Holden, H.M.,Raushel, F.M.; Biosynthesis of d- glycero -l- gluco -Heptose in the Capsular Polysaccharides of Campylobacter jejuni .; Biochemistry, 60:1552-1563, 2021; PubMed: 33900734; DOI: 10.1021/acs.biochem.1c00183

Experimental method

X-RAY DIFFRACTION (1.85 Å)