7KGZ

FMN-binding beta-glucuronidase from Roseburia hominis

Summary for 7KGZ

• Entry DOI: 10.2210/pdb7kgz/pdb
• Descriptor: Beta-glucuronidase, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: beta-glucuronidase, gut microbial enzyme, fmn, hydrolase
• Biological source: Roseburia hominis
• Total number of polymer chains: 2
• Total formula weight: 167770.74

Authors

Walker, M.E.,Redinbo, M.R. (deposition date: 2020-10-19, release date: 2021-11-10, Last modification date: 2023-10-18)

• Primary citation: Zhang, J.,Walker, M.E.,Sanidad, K.Z.,Zhang, H.,Liang, Y.,Zhao, E.,Chacon-Vargas, K.,Yeliseyev, V.,Parsonnet, J.,Haggerty, T.D.,Wang, G.,Simpson, J.B.,Jariwala, P.B.,Beaty, V.V.,Yang, J.,Yang, H.,Panigrahy, A.,Minter, L.M.,Kim, D.,Gibbons, J.G.,Liu, L.,Li, Z.,Xiao, H.,Borlandelli, V.,Overkleeft, H.S.,Cloer, E.W.,Major, M.B.,Goldfarb, D.,Cai, Z.,Redinbo, M.R.,Zhang, G.; Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.; Nat Commun, 13:136-136, 2022; PubMed: 35013263; DOI: 10.1038/s41467-021-27762-y

Experimental method

X-RAY DIFFRACTION (2.4 Å)